Biosensor For the Real-Time Imaging of Manganese(II) in Cells
Biosensors have been around since Leland C. Clark Jr. first successfully developed a ‘true’ biosensor for oxygen detection in the 1950s. Since then, biosensors have taken on a key role in important biomedical applications such as drug discovery, disease monitoring, and identifying biomarkers in bodily fluids (blood, saliva, sweat, urine) that may be indicators of disease.
Selective Biosensing
The breakthrough by the Penn State team could herald a series of new advances in biotechnological applications with the potential to promote knowledge-building while laying the foundations for a new approach to further study the physiology of manganese. The team was able to construct the genetically encoded biosensors by reprogramming LanM to construct the scaffolds, which could then detect levels of manganese(II) at physiologically relevant concentrations.
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3rd Editonal of International Conference on Sensing Technology | 27-28 Mar 2023 | Malaysia
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